Systemic Lupus Erythematosus

<p>A 28-year-old woman is evaluated for fatigue, a photosensitive malar rash, and nonerosive arthritis. Serologic testing is ordered. Which of the following autoantibodies is the <strong>most specific</strong> for systemic lupus erythematosus?</p>

<p>A 34-year-old woman with established SLE presents for a routine follow-up visit. She feels well and has no edema, hypertension, or urinary symptoms. Which of the following is the most appropriate screening for lupus nephritis at this visit?</p>

<p>A 22-year-old woman is newly diagnosed with mild SLE manifesting as arthralgias and a photosensitive rash. Which of the following medications should be initiated in <strong>all</strong> patients with SLE unless specifically contraindicated?</p>

<p>A 30-year-old woman with SLE develops hypertension, an active urinary sediment, and a urine protein-to-creatinine ratio of 3.5 g/g. Renal biopsy shows diffuse (class IV) proliferative lupus nephritis. Which of the following is the most appropriate initial induction therapy?</p>

<p>A 29-year-old woman with SLE, currently taking mycophenolate mofetil and hydroxychloroquine, wishes to become pregnant. Her disease has been quiescent for 8 months. Which of the following is the most appropriate management?</p>